All are true for Contact lenses except:

A Contact lenses are a major risk factor for microbial keratitis.
B Contact lens use is the most common risk factor for corneal infections in the industrialized world.
C Long-term contact lens wear inhibits epithelial cell proliferation and migration and suppresses limbal stem cell production of basal corneal epithelial cells.
D Soft contact lenses, do not alter the microenvironment of the ocular surface.

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