Katrina has an abnormal result on a Papanicolaou test. After admitting that she read her chart while the nurse was out of the room, Katrina asks what dysplasia means. Which definition should the nurse provide?

A Presence of completely undifferentiated tumor cells that don’t resemble cells of the tissues of their origin.
B Increase in the number of normal cells in a normal arrangement in a tissue or an organ.
C Replacement of one type of fully differentiated cell by another in tissues where the second type normally isn’t found.
D Alteration in the size, shape, and organization of differentiated cells.